SLC27A3
Function
Mainly functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:23936004). Can mediate the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across membranes (By similarity).
Sequence Similarities
Belongs to the ATP-dependent AMP-binding enzyme family.
Tissue Specificity
Expressed in bronchial and bronchiolar epithelial cells (at protein level).
Cellular localization
- Mitochondrion membrane
- Single-pass membrane protein
Alternative names
ACSVL3, FATP3, PSEC0067, UNQ367/PRO703, SLC27A3, Long-chain fatty acid transport protein 3, FATP-3, Fatty acid transport protein 3, Arachidonate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 3, Very long-chain acyl-CoA synthetase homolog 3, VLCS-3