SLC37A1

Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.

Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.

Expressed in numerous tissues, with highest expression in pancreas, kidney, bone marrow, spleen, liver, small intestine, as well as in fetal brain, liver and spleen.

• Endoplasmic reticulum membrane
• Multi-pass membrane protein

G3PP, SLC37A1, Glucose-6-phosphate exchanger SLC37A1, Glycerol-3-phosphate permease, Solute carrier family 37 member 1, G-3-P permease

• entrezGene:54020
• omim:608094
• swissprot:P57057

Proteins

Immunology & Infectious Disease

57648Da