Slc6a11
Function
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:1400419, PubMed:1497897). Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).
Sequence Similarities
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.
Tissue Specificity
Brain and retina (PubMed:1400419, PubMed:1497897). Expressed predominantly within neurons (PubMed:1497897). Expressed in the hippocampus (at protein level) (PubMed:8731228).
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
Gabt3, Gat-3, Gat-b, Slc6a11, Sodium- and chloride-dependent GABA transporter 3, GAT-3, Solute carrier family 6 member 11