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Function

Golgi Na(+), K(+)/(H+) antiporter. Mediates the electoneutral influx of Na(+) or K(+) in exchange for H(+). May contribute to the regulation of Golgi apparatus volume and pH.

Involvement in disease

Intellectual developmental disorder, X-linked 108

MRX108

A form of intellectual disability, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked forms, while syndromic forms present with associated physical, neurological and/or psychiatric manifestations.

None

The disease is caused by variants affecting the gene represented in this entry.

Post-translational modifications

N-glycosylated.

Sequence similarities

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Tissue specificity

Ubiquitously expressed.

Cellular localization

  • Golgi apparatus
  • trans-Golgi network membrane
  • Multi-pass membrane protein
  • Recycling endosome membrane
  • Multi-pass membrane protein
  • Cell membrane
  • Multi-pass membrane protein

Alternative names

NHE7, SLC9A7, Sodium/hydrogen exchanger 7, Na(+)/H(+) exchanger 7, Solute carrier family 9 member 7, NHE-7

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

80131Da

We found 1 product in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'SLC9A7' (1)

Products