Expressed during differentiation of squamous cells.
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Belongs to the cornifin (SPRR) family.
Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
Small proline-rich protein 2B, SPR-2B, SPRR2B
Proteins
Oncology
7975Da
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