SMCP
Developmental stage
Expressed in postmeiotic cells.
Function
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity).
Tissue Specificity
Testis. Is selectively expressed in the spermatids of seminiferous tubules.
Cellular localization
- Cytoplasm
- Mitochondrion membrane
- Peripheral membrane protein
- Cytoplasmic side
- Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis.
Alternative names
MCS, MCSP, SMCP, Sperm mitochondrial-associated cysteine-rich protein