SNRK
Function
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
Post-translational modifications
Autophosphorylated. Phosphorylation on Thr-173 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39.
Sequence Similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Tissue Specificity
Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.
Cellular localization
- Nucleus
Alternative names
KIAA0096, SNFRK, SNRK, SNF-related serine/threonine-protein kinase, SNF1-related kinase