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Function

Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:30315277, PubMed:30705154). Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome (PubMed:16723661, PubMed:26912367, PubMed:9774689). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).

Cellular localization

  • Nucleus

Alternative names

PRP8BP, SFP38, WDR57, SNRNP40, U5 small nuclear ribonucleoprotein 40 kDa protein, U5 snRNP 40 kDa protein, U5-40K, 38 kDa-splicing factor, Prp8-binding protein, U5 snRNP-specific 40 kDa protein, WD repeat-containing protein 57, hPRP8BP

Target type

Proteins

Primary research area

Metabolism

Molecular weight

39311Da

We found 3 products in 2 categories

Primary Antibodies

Target

Application

Reactive species

Cell Lines & Lysates

Target

Cell type

Species or organism