Sodium/potassium-transporting ATPase subunit beta-2
Domain
The C-terminal lobe folds into an immunoglobulin-like domain and mediates cell adhesion properties.
Function
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.
Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
Sequence Similarities
Belongs to the X(+)/potassium ATPases subunit beta family.
Cellular localization
- Cell membrane
- Single-pass type II membrane protein
Alternative names
Sodium/potassium-transporting ATPase subunit beta-2, Adhesion molecule in glia, Sodium/potassium-dependent ATPase subunit beta-2, AMOG, ATP1B2