SOX1
Domain
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Function
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Tissue Specificity
Mainly expressed in the developing central nervous system.
Cellular localization
- Nucleus
Alternative names
Transcription factor SOX-1, SOX1