SP2
Domain
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In SP2, the motif is inactive.
Function
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
Sequence Similarities
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Cellular localization
- Nucleus
Alternative names
KIAA0048, SP2, Transcription factor Sp2