spaP
Domain
A short internal peptide (residues 452-470) has been used as a miniprotein to examine protein folding and stability.
Function
Surface protein antigen implicated in dental caries.
Post-translational modifications
Detected as a 185 kDa cell surface protein, but also as 2 proteins in S.mutans culture supernatants of about 150 kDa (antigen I) and 50 kDa (antigen II); antigen II is only seen after proteolysis. Antigen I and II have the same N-terminus but different C-termini.
Sequence Similarities
Belongs to the antigen I/II family.
Cellular localization
- Secreted
- Cell wall
- Peptidoglycan-anchor
Alternative names
SMU_610, Peri, Plin, Plin1, Cell surface antigen I/II