Spint1
Domain
This inhibitor contains two inhibitory domains.
Function
Inhibitor of HGFAC (By similarity). Inhibits serine protease activity of ST14/matriptase in vitro (By similarity). Inhibits serine protease activity of TMPRSS13, via the BPTI/Kunitz inhibitor 1 domain (By similarity).
Cellular localization
- Secreted
- Cytoplasm
- Cell membrane
Alternative names
Hai1, Spint1, Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1