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SRP14

Function

Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:11089964). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:11089964). The complex of SRP9 and SRP14 is required for SRP RNA binding (PubMed:11089964).

Sequence Similarities

Belongs to the SRP14 family.

Cellular localization

Alternative names

Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein

swissprot:P37108 entrezGene:6727 omim:600708