SSTR1

Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.

Belongs to the G-protein coupled receptor 1 family.

Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.

• Cell membrane
• Multi-pass membrane protein

Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SST1, SRIF-2, SSTR1

• entrezGene:6751
• omim:182451
• swissprot:P30872

Proteins

Oncology

42686Da