SSU72
Function
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK.
Sequence Similarities
Belongs to the SSU72 phosphatase family.
Cellular localization
- Nucleus
- Cytoplasm
- Predominantly in the cytosol.
Alternative names
HSPC182, PNAS-120, SSU72, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, CTD phosphatase SSU72