ST6GAL1

Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.

Protein modification; protein glycosylation.

The soluble form derives from the membrane form by proteolytic processing.

The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.

N-glycosylated.

Belongs to the glycosyltransferase 29 family.

• Golgi apparatus
• Golgi stack membrane
• Single-pass type II membrane protein
• Secreted
• Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

SIAT1, ST6GAL1, B-cell antigen CD75, ST6Gal I, Sialyltransferase 1, ST6GalI

• entrezGene:6480
• omim:109675
• swissprot:P15907

Proteins

Immunology & Infectious Disease

46605Da