Skip to main content

Function

Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.

Post-translational modifications

O-glycosylated.

Sequence similarities

Belongs to the glycosyltransferase 29 family.

Tissue specificity

Weakly expressed in some tissues, such as small intestine, colon and fetal brain.

Cellular localization

  • Golgi apparatus
  • Golgi stack membrane
  • Single-pass type II membrane protein

Alternative names

KIAA1877, SIAT2, ST6GAL2, ST6Gal II, Sialyltransferase 2, ST6GalII, hST6Gal II

Target type

Proteins

Primary research area

Oncology

Molecular weight

60158Da

We found 2 products in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'ST6GAL2' (2)

Products