St6galnac2
Function
Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins (PubMed:8662927). Shows a preference for N-acetylgalactosamine (GalNAc) residues already modified by the addition of galactose or galactose followed by sialic acid in alpha-2,3 linkage (PubMed:8662927).
Pathway
Protein modification; protein glycosylation.
Sequence Similarities
Belongs to the glycosyltransferase 29 family.
Tissue Specificity
Highly expressed in lactating mammary gland and adult testis. Lower levels in kidney.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
Siat7, Siat7b, St6galnac2, ST6GalNAc II, Sialyltransferase 7B, ST6GalNAcII, SIAT7-B