ST8SIA5
Function
Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively.
Pathway
Protein modification; protein glycosylation.
Sequence Similarities
Belongs to the glycosyltransferase 29 family.
Tissue Specificity
Isoform 1
Expressed in fetal and adult brain, adult heart and skeletal muscle.
Isoform 2
Expressed in fetal and adult brain, not detected in adult heart and skeletal muscle.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
SIAT8E, ST8SIA5, Sialyltransferase 8E, Sialyltransferase St8Sia V, SIAT8-E, ST8SiaV