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STAP1

Function

In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.

Post-translational modifications

Phosphorylated on tyrosine by TEC. Phosphorylated on tyrosine by KIT (By similarity).

Cellular localization

Alternative names

BRDG1, STAP1, Signal-transducing adaptor protein 1, STAP-1, BCR downstream-signaling protein 1, Docking protein BRDG1, Stem cell adaptor protein 1

swissprot:Q9ULZ2 omim:604298 entrezGene:26228