STARD13
Function
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Tissue Specificity
Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
Cellular localization
- Cytoplasm
- Membrane
- Peripheral membrane protein
- Cytoplasmic side
- Mitochondrion membrane
- Peripheral membrane protein
- Cytoplasmic side
- Lipid droplet
Alternative names
DLC2, GT650, STARD13, StAR-related lipid transfer protein 13, 46H23.2, Deleted in liver cancer 2 protein, Rho GTPase-activating protein, START domain-containing protein 13, DLC-2, StARD13