STARD13

GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.

Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.

• Cytoplasm
• Membrane
• Peripheral membrane protein
• Cytoplasmic side
• Mitochondrion membrane
• Peripheral membrane protein
• Cytoplasmic side
• Lipid droplet

DLC2, GT650, STARD13, StAR-related lipid transfer protein 13, 46H23.2, Deleted in liver cancer 2 protein, Rho GTPase-activating protein, START domain-containing protein 13, DLC-2, StARD13

• entrezGene:90627
• omim:609866
• swissprot:Q9Y3M8

Proteins

Oncology

124967Da