STC1
Function
Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.
Sequence Similarities
Belongs to the stanniocalcin family.
Tissue Specificity
Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes and adrenal medulla.
Cellular localization
- Secreted
Alternative names
STC, STC1, Stanniocalcin-1, STC-1