STEAP1

Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4.

Belongs to the STEAP family.

Ubiquitously expressed. Highly expressed in prostate tumors.

• Endosome membrane
• Multi-pass membrane protein
• Cell membrane
• Multi-pass membrane protein

PRSS24, STEAP, STEAP1, STEAP1 protein, Six-transmembrane epithelial antigen of prostate 1

• entrezGene:26872
• omim:604415
• swissprot:Q9UHE8

Proteins

Oncology

39851Da