STMN3
Function
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Post-translational modifications
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.
Sequence Similarities
Belongs to the stathmin family.
Tissue Specificity
Neuron specific.
Cellular localization
- Golgi apparatus
- Cell projection
- Growth cone
- Cell projection
- Axon
- Cytoplasm
- Cytosol
Alternative names
SCLIP, STMN3, Stathmin-3, SCG10-like protein