STRIP1
Function
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation.
Sequence Similarities
Belongs to the STRIP family.
Cellular localization
- Cytoplasm
- Enriched on the plasma membrane.
Alternative names
FAM40A, KIAA1761, STRIP1, Striatin-interacting protein 1, Protein FAM40A