Syntaxin 8

Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.

Ubiquitinated by HECTD3.

Belongs to the syntaxin family.

Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.

• Membrane
• Single-pass type IV membrane protein
• Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity).

Syntaxin-8, STX8

• entrezGene:9482
• omim:604203
• swissprot:Q9UNK0

Proteins

Neuroscience

26907Da