SULT1A3

Function

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

Post-translational modifications

The N-terminus is blocked.

Sequence Similarities

Belongs to the sulfotransferase 1 family.

Tissue Specificity

Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

Cellular localization

• Cytoplasm

Alternative names

STM, SULT1A3, Sulfotransferase 1A3, ST1A3, Aryl sulfotransferase 1A3/1A4, Catecholamine-sulfating phenol sulfotransferase, HAST3, M-PST, Monoamine-sulfating phenol sulfotransferase, Placental estrogen sulfotransferase, Sulfotransferase 1A3/1A4, Thermolabile phenol sulfotransferase, TL-PST

Database links

swissprot:P0DMM9 entrezGene:445329 omim:600641 swissprot:P0DMN0 swissprot:P50224 entrezGene:6818