Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. Required for ultrasonic vocalizations.
Contains chondroitin sulfate chains.
Expressed in angiogenic endothelial cells (at protein level).
Sushi repeat-containing protein SRPX2, Srpx2
Proteins
Oncology
53140Da
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