Synaptobrevin homolog YKT6

The longin domain regulates palmitoylation and membrane targeting.

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

Palmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting.

Farnesylation is required for Golgi targeting.

Belongs to the synaptobrevin family.

• Cytoplasm
• Cytosol
• Cytoplasmic vesicle membrane
• Lipid-anchor
• Cytoplasmic side
• Golgi apparatus membrane
• Lipid-anchor
• Cytoplasmic side
• Probably cycles through vesicles between Golgi and endosomes.

Synaptobrevin homolog YKT6, YKT6

• entrezGene:10652
• omim:606209
• swissprot:O15498

Proteins

Neuroscience

22418Da