Synaptopodin

Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).

O-glycosylated.

Belongs to the synaptopodin family.

Expressed in cerebral cortex.

• Cytoplasm
• Cytoskeleton
• Cell junction
• Tight junction
• Perikaryon
• Cell projection
• Dendritic spine
• Postsynaptic density
• Synapse
• Cytoplasm
• Cytosol
• Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.

KIAA1029, SYNPO, Synaptopodin

• entrezGene:11346
• omim:608155
• swissprot:Q8N3V7

Proteins

Neuroscience

99463Da