Syntaxin-binding protein 3

Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.

Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.

Belongs to the STXBP/unc-18/SEC1 family.

Megakaryocytes and platelets.

• Cytoplasm
• Cytosol
• Cell membrane
• In platelets, predominantly cytosolic. Low amounts membrane-associated.

Syntaxin-binding protein 3, Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, PSP, Unc18-3, Unc-18C, STXBP3

• entrezGene:6814
• omim:608339
• swissprot:O00186

Proteins

Neuroscience

67764Da