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Domain

The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.

Function

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane (By similarity). Involved in the regulation of short-term and long-term synaptic plasticity.

Post-translational modifications

Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.

Phosphorylated by SRC.

Sequence similarities

Belongs to the synaptophysin/synaptobrevin family.

Cellular localization

  • Cytoplasmic vesicle
  • Secretory vesicle
  • Synaptic vesicle membrane
  • Multi-pass membrane protein
  • Synapse
  • Synaptosome

Alternative names

Synaptophysin, BM89 antigen, Major synaptic vesicle protein p38, Syp

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

34025Da

We found 1 product in 1 category

Assay Kits

Reactive species

Detection method

Search our catalogue for 'SYP' (1)

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