TACR2
Function
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
NK2R, NKNAR, TAC2R, TACR2, Substance-K receptor, SKR, NK-2 receptor, Neurokinin A receptor, Tachykinin receptor 2, NK-2R