May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Glycosylation at Asn-198 is crucial for protein stability.
Belongs to the EPCAM family.
CD326, EPCAM, TACSTD1, Epithelial cell adhesion molecule, Ep-CAM, Tumor-associated calcium signal transducer 1
Proteins
Oncology
34879Da
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