TADA3
Function
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Sequence Similarities
Belongs to the NGG1 family.
Tissue Specificity
Ubiquitously expressed.
Cellular localization
- Nucleus
Alternative names
ADA3, TADA3L, TADA3, Transcriptional adapter 3, ADA3 homolog, STAF54, Transcriptional adapter 3-like, hADA3, ADA3-like protein