TAPBPL
Function
Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC).
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
- Microsome membrane
- Single-pass type I membrane protein
- Golgi apparatus membrane
- Single-pass type I membrane protein
- Mainly found in endoplasmic reticulum but a minority is found on the cell surface (PubMed:11920573).
Alternative names
Tapasin-related protein, TAPASIN-R, TAP-binding protein-like, TAP-binding protein-related protein, Tapasin-like, TAPBP-R, TAPBPL