TCN1
Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Post-translational modifications
Contains about 30% carbohydrates.
Sequence Similarities
Belongs to the eukaryotic cobalamin transport proteins family.
Tissue Specificity
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Cellular localization
- Secreted
Alternative names
TC1, TCN1, Transcobalamin-1, TC-1, Haptocorrin, Protein R, Transcobalamin I, HC, TC I, TCI