TESK2
Function
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Sequence Similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Tissue Specificity
Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells.
Cellular localization
- Nucleus
Alternative names
Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2