Tf
Function
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Sequence Similarities
Belongs to the transferrin family.
Tissue Specificity
Expressed by the liver and secreted in plasma.
Cellular localization
- Secreted
Alternative names
Serotransferrin, Transferrin, Beta-1 metal-binding globulin, Liver regeneration-related protein LRRG03, Siderophilin, Tf