Tff3

Developmental stage

No expression found in embryos.

Function

Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).

Tissue Specificity

Expressed in goblet cells of the intestines and colon (at protein level). Expressed abundantly in goblet cells of intestine and colon, and at low levels in stomach. No expression in brain, lung, spleen, kidney, uterus, pancreas, liver, heart or thymus.

Cellular localization

• Secreted
• Extracellular space
• Extracellular matrix
• Cytoplasm

Alternative names

Itf, Tff3, Trefoil factor 3, Intestinal trefoil factor, mITF

Database links

swissprot:Q62395 entrezGene:21786

Other research areas

• Oncology