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Domain

This inhibitor contains three inhibitory domains.

Function

May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.

Tissue specificity

Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.

Cellular localization

  • Secreted

Alternative names

Tissue factor pathway inhibitor 2, TFPI-2, Placental protein 5, PP5, TFPI2

Target type

Proteins

Primary research area

Oncology

Molecular weight

26934Da

We found 8 products in 3 categories

Primary Antibodies

Target

Reactive species

Assay Kits

Target

Reactive species

Detection method

Proteins & Peptides

Target

Species of origin