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TGDS

Involvement in disease

Catel-Manzke syndrome

CATMANS

A syndrome characterized by Pierre Robin sequence and a unique form of bilateral hyperphalangy causing a clinodactyly of the index finger. Pierre Robin sequence includes an opening in the roof of the mouth (a cleft palate), a large tongue (macroglossia), and a small lower jaw (micrognathia).

None

The disease is caused by variants affecting the gene represented in this entry.

Sequence Similarities

Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

Alternative names

TGDS

swissprot:O95455 entrezGene:23483