TGOLN2
Function
May be involved in regulating membrane traffic to and from trans-Golgi network.
Tissue Specificity
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Golgi apparatus
- trans-Golgi network membrane
- Single-pass type I membrane protein
- Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.
Alternative names
TGN46, TGN51, TGOLN2, Trans-Golgi network integral membrane protein 2, Trans-Golgi network glycoprotein 46, Trans-Golgi network glycoprotein 48, Trans-Golgi network glycoprotein 51, Trans-Golgi network protein 2, TGN38 homolog, hTGN46, hTGN48, hTGN51