THAP12

Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.

DAP4, P52RIPK, PRKRIR, THAP0, THAP12, 52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, THAP domain-containing protein 12, p58IPK-interacting protein

• entrezGene:5612
• omim:607374
• swissprot:O43422

Proteins

87704Da