Thsd1
Function
Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
Tissue Specificity
Expressed in cerebral vascular endothelium.
Cellular localization
- Endosome membrane
- Single-pass type I membrane protein
- Cell junction
- Focal adhesion
- Localizes to nascent focal adhesions.
Alternative names
Tmtsp, Thsd1, Thrombospondin type-1 domain-containing protein 1, Transmembrane molecule with thrombospondin module