TIMM17B
Function
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Post-translational modifications
Forms one disulfide bond.
Sequence Similarities
Belongs to the Tim17/Tim22/Tim23 family.
Tissue Specificity
Expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver.
Cellular localization
- Mitochondrion inner membrane
- Multi-pass membrane protein
Alternative names
TIM17B, JM3, TIMM17B, Mitochondrial import inner membrane translocase subunit Tim17-B