Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
The activity of TIMP2 is dependent on the presence of disulfide bonds.
Belongs to the protease inhibitor I35 (TIMP) family.
Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Proteins
Oncology
24399Da
We found 33 products in 4 categories
ab230511
ab180630
ab238062
ab287940
ab53730
ab100653