TIMP2
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them.
Post-translational modifications
The activity of TIMP2 is dependent on the presence of disulfide bonds.
Sequence Similarities
Belongs to the protease inhibitor I35 (TIMP) family.
Cellular localization
- Secreted
Alternative names
TIMP-2, TIMP2, Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2