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Talin 1

OverviewProducts

Function

Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).

Cellular localization

  • Cell projection
  • Ruffle membrane
  • Peripheral membrane protein
  • Cytoplasmic side
  • Cytoplasm
  • Cytoskeleton
  • Cell surface
  • Cell junction
  • Focal adhesion
  • Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).

Alternative names

  • Talin-1
  • KIAA1027
  • TLN
  • TLN1

Database links

Target type

Proteins

Primary research area

Oncology

Molecular weight

269767Da